Two Days in Prague: A Perfect Weekend Itinerary

This two-day Prague itinerary is packed with ideas for what to do if you’re in Prague for a weekend or a couple of days mid-week. 

There’s so much to see in Prague that two days isn’t enough time to take it all in. However, since Prague is such a walkable city, you can maximize your time and see a lot!

The beautiful historic center of Prague is a UNESCO World Heritage Site. Because this historic area escaped demolition in World War II, it retained its medieval layout, historic monuments, and traditional charm. 

If it’s your first time to Prague, this is the perfect 2 day itinerary to introduce you to this lovely city!

I’ve filled this Prague Two-Day itinerary with plenty of sites and activities to easily fill two days!

Two Days in Prague Itinerary

Get ready, because this two-day itinerary for Prague is packed! There’s a lot to do in the capital of the Czech Republic, so this itinerary is full of attractions and sites! You’ll have to pick and choose which must-see spots match your interests!

Day 1: Malá Strana & Hradcany

On your first day in Prague, explore Malá Strana (Lesser Town) and Hradcany (the Castle District).

Malá Strana (Lesser Town)

First, if possible, wake up early and head to the Charles Bridge. You’ll appreciate seeing the bridge before it’s full of tourists. Then, head to Malá Strana.

John Lennon Wall

Swing by the John Lennon Wall on your way to Kampa Island.  After John Lennon was killed in 1980, the colorful mural was created to celebrate peace, love, hope, and freedom. The wall changes constantly.

Kampa Park

At Kampa Park you’ll find great riverside views of the Charles Bridge and the Old Town. Don’t miss the exhibition of Prague’s famous yellow penguins.

In Kampa Park, look for David Cerny’s “Crawling Babies” statues.

Museum Kampa

If you like contemporary art, stop at Museum Kampa to enjoy the remarkable collection of modern art.

Petrín Hill

Next, head up to Petrin Hill. You’ll have to walk or take a tram. The Petrín Hill funicular is out of commission while the slope is stabilized, and will hopefully reopen summer 2026.

Check out Petrin Tower, inspired by the Eiffel Tower, for incredible views of Prague. And you might also like the Mirror Maze.

Hradcany (Castle District)

Strahov Monastery

Next, head to Strahov Monastery, where you can stroll through the abbey’s gardens for more stunning views of Prague.

Book lovers will want to peek into the spectacular baroque Strahov Library. You can also tour the oldest parts of the monastery and enjoy the art gallery.

Prague Castle

Next, head to Prague’s most famous landmark: Prague Castle! The Prague castle complex is the largest castle complex in the world.

Prague Castle has been the seat of power for Czech rulers, including Bohemian kings, Holy Roman Emperors, and the presidents of the Czechoslovakia and the Czech Republic.

As you might expect, the castle complex has been expanded and renovated over the centuries, so the architecture reflects a mix of Romanesque, Gothic, Renaissance, and Baroque styles.

You can take a private tour of Prague Castle to learn more about the architecture and history of the Castle, as well as the people who lived there.

St. Vitus Cathedral

The beautiful Gothic St Vitus Cathedral is the centerpiece of Prague Castle. It’s known for it’s beautiful stained glass windows, being the burial place of many kings and emperors, and housing the Czech Republic’s cursed Crown Jewels (only rarely displayed).

If your legs are up for it, climb the 287 stairs to the top of the bell tower for an even more incredible view!

Golden Lane

Lined with small houses that originally housed castle guards and craftsmen, the buildings along the Golden Lane now hold exhibit spaces, galleries, and shops. Kafka lived (and wrote) at Number 22.

St. George’s Basilica

This strikingly austere Romanesque church dates to the 10th century, making it one of Prague’s oldest churches.

Old Royal Palace

The Gothic vaulted ceiling of Vladislav Hall is visually stunning and an architectural marvel. Perhaps most unusual is the Defenestration Room, so-called because two Catholic officials were thrown out of its windows in 1618.

The Story of Prague Castle

This exhibition tells the thousand-year history of Prague Castle through artifacts and stories of the people who have lived and worked there.

Back to Mala Strana

After leaving the castle, head downhill along Nerudova.

St. Nicholas Church

Walk around Malostranske nam to see the High Baroque St. Nicholas Church. A masterpiece of Baroque architecture, this church has one of the highest domes in Prague.

The interior is ornate and grand, with a stunning altar, gilded statues, and an organ played by Mozart in 1787. Classical music concerts are sometimes held here.

Wallenstein Garden

Next, head to the Wallenstein Garden to enjoy formal lawns, fountains, plantings, and statues.

Kafka Museum

Next, make your way past the “Piss” sculpture, right by the Franz Kafka museum. If you want to visit the museum, you’ll see letters and diaries written by Kafka, as well as photos and artifacts. 

Dinner in Prague

Finally end your day with an unforgettable dinner experience:

Jazz Boat Dinner Cruise: Enjoy evening views of Prague’s stunning monuments, live music, and a delicious dinner on this river cruise. There is an early and late cruise time, to suit your preferred dining time.

Mozart Concert with Dinner: Set in the historical Boccaccio Ballroom, this dinner features a three-course Czech and Austrian menu. You’ll hear music from Mozart’s operas performed by professional musicians.

Private Prague Food and Drinks Tour: Book a dinner tour of Prague with your private guide who will introduce you to Czech specialties at the best local restaurants.

Day 2: Staré Město, Josefov & Nové Město

On your second day in Prague, explore the Staré Město (Old Town), Josefov (Jewish Quarter), and Nové Město (New Town).

Staré Město (Old Town)

Start your day in Prague’s Old Town, walking through narrow, cobblestoned streets that date to medieval times.

Old Town Walking Tour

To really learn about the area you’re seeing, take a walking tour of the Old Town area. This walking tour is absolutely the best way to learn about Prague’s history.

Prague’s Old Town Square

Prague’s Old Town Square is the heart of the Old Town. Originally Prague’s central marketplace, the square today still serves as a marketplace, as well as a meeting place, concert venue, and festival space.

Church of Our Lady before Týn

The twin spires of the iconic Church of Our Lady before Týn dominate the square’s skyline. Built in the 14th century, the church houses the tomb of Tycho Brahe, the father of modern astronomy who also dabbled in alchemy and astrology.

St. Nicholas Church

In the Old Town Square, St. Nicholas Church was built in the 18th Century as part of a Benedictine monastery. Inside, you’ll find many intricate frescoes depicting the life of St. Nicholas and biblical scenes. The church also hosts classical music concerts.

Old Town Hall

Established in 1338, the Old Town Hall complex includes the a tower with an observation deck, Gothic chapel, state rooms, and a medieval underground complex.

Prague Astronomical Clock

Every hour on the hour, between 9 a.m. and 9 p.m, the Prague Astronomical Clock at the Old Town Hall chimes and parades the 12 apostles through the windows above the elaborate clock, as Death rings in the hour.

Powder Tower

A few blocks from the Old Town Square, you’ll find the Powder Tower, one of Prague’s original city gates, which dates to the 15th century.

Josefov (Jewish Quarter)

Next, head to Prague’s Jewish Quarter, one of the best-preserved Jewish areas in Europe. Jews settled in Prague as early as the 10th century, and were ordered to settle into the Jewish ghetto in the 13th century.

Situated between the Vltava River and Prague’s Old Town Square, Josetov contains multiple synagogues, a cemetery, and exhibits that offer insight into Jewish life in Prague throughout history.

Walking Tour of the Jewish Quarter

For truly meaningful perspective on the Jewish Quarter of Prague, take a walking tour. You’ll get to see the synagogues and the museum, but more importantly, you’ll learn about the history of Jewish life in Prague on this powerful guided tour.

Prague Jewish Museum

The Prague Jewish Museum includes multiple sites and uses Jewish artifacts, art, and documents to tell the story of Jewish life and culture in Prague and the Czech Republic at large.

Tickets include admission to the Old-New Synagogue, the Old Jewish Cemetery, the Spanish Synagogue, Maisel Synagogue, and Pinkas Synagogue, as well as temporary exhibitions. Note: The Jewish Museum in Prague is closed Saturdays and Jewish holidays.

Franz Kafka Monument

Look for the Franz Kafka Monument right beside the Spanish Synagogue. Inspired by his story “Description of a Struggle,” the statue depicts Kafka on the shoulders of a headless figure.

Nové Město (New Town)

The New Town isn’t really that new, but it’s all relative! New Town is the commercial heart of Prague, and you’ll find plenty of restaurants, bars, shops, and museums to visit.

Wenceslas Square

Then make your way to Wenceslas Square, the location of many demonstrations and gatherings throughout Prague’s history.

You’ll see the statue of Saint Wenceslas, the patron saint of Bohemia, at the top of the square.

The Jan Palach Memorial is harder to find. Near the steps of the National Museum, look for a simple bronze cross embedded in the pavement that memorializes his act of resistance to Soviet control of Czechoslovakia.

There are so many museums to see in Prague’s New Town. If you only have two days in Prague, you won’t be able to see them all, so choose the best places for you, based on your interests!

national Museum

Learn about Czech culture and history at the National Museum. The extensive collection covers social history, natural history, archaeology, and more.

City of Prague Museum

Learn about the City of Prague from prehistoric times to the present day. Artifacts include artworks, archaeological finds, and a model of Prague.

Museum of Communism

The Museum of Communism looks at life in Czechoslovakia under the communist regime from 1948 to 1989. You’ll see reconstructed apartments, classrooms, and interrogation rooms. For me personally, this was one of my favorite museums, because I felt like it captured the emotion of that era.

Mucha Museum

The Mucha Museum features work by Czech Art Nouveau artist Alphonse Mucha. The collection includes posters, lithographs, and other artwork with his signature ethereal dreaminess.

And when you’re finished with museums, be sure to see these:

Lucerna Passage

Check out Lucerna passage, a short walk from Wenceslas Square. This grand arcade features a famous statue of Wenceslas astride a an upside down, dead horse. 

Head of Franz Kafka

Kafka’s Rotating Head reflects Kafka’s common themes of alienation, identity, inner conflict, and transformation. Layers of stainless steel rotate independently, periodically aligning to reveal Kafka’s face.

Dancing House

Finally, head to the Dancing House, designed by Frank Gehry and Vlado Miluni. If you arrive late, don’t worry–it looks great lit up after dark. End your day with dinner or drinks at a the Glass Bar on the top floor, overlooking the river.

Where to stay in Prague

No matter what type of accommodations you’re looking for, you’ll find it in Prague. Here are my top picks.

Best hotels in Prague

Here are some of the best hotels in Prague, all centrally located and luxuriously comfortable.

The Grand Mark Prague: This incredible hotel is located in a 17th century residential palace in the heart of Prague. It has a spa and its own gardens.

Three Storks: This hotel features modern design in a 14th century building that was once a monastery’s brewery!

The Julius Prague: This five-star hotel offers modern amenities in a gorgeous historic building.

Alchymist Grand Hotel and Spa: Pamper yourself with a stay here. You’ll love the spa, sauna, and turn-down service with chocolate pralines!

Art Nouveau Palace Hôtel: A five-star hotel with luxurious rooms and an outstanding breakfast.

Best holiday rentals in Prague

If you’d prefer a vacation rental, here are listings you’ll love.

Old Town Square Luxury Apartment: You’ll have a view of the Old Town Hall clock from this sunny apartment! Sleeps 6.

4 Rooms – City Center: This rental has two balconies where you can relax! Sleeps 6.

Cozy Stay in Old Prague: This airy apartment in the heart of Prague features a well-equipped kitchen with a coffee machine. Sleeps 7.

Baroque Gem: This quiet apartment in a historic home has a private terrace, a coffee machine, and space for everyone. Sleeps 8.

The Karoline: Old world charm meets modern comfort, in this newly renovated flat. Sleeps 8.

What to pack for Prague

No matter, the season, pack comfortable shoes that can handle Prague’s cobblestone streets.

Prague is hot in summer, so wear lightweight clothing, sundresses, shorts and T-shirts.

In fall and spring, wear layers. You’ll probably want long pants or skirts. And remember a lightweight jacket!

In winter, prepare for cold, snowy weather. Bring boots or sturdy walking shoes, long pants, sweaters, and a coat, plus a hat and gloves!

Getting around Prague

Prague is a relatively small city, extremely walkable. In fact, you’ll almost certainly find yourself retracing your steps at some point as you walk through the city. 

Prague’s public transportation includes a tram, bus, and metro system.

Nine bridges straddle the Vltava River, connecting both sides of city. Prague city center and the surrounding areas are divided into nine districts, each containing several different neighborhoods.

Best Time to Visit Prague

These days, Prague is an extremely popular tourist destination. Do yourself a favor and visit during the spring or fall, when you can enjoy the city’s beauty with fewer crowds. During the summer months, Prague is packed with tourists!

Final Thoughts on Two Days in Prague

Once you’ve spent a few weekdays or a weekend in Prague, you’ll know that two days is simply not enough time in this beautiful, historic city.

With its fairytale architecture, whimsical public art displays, and fascinating history, Prague is a captivating city.

However, you can see a lot in two days in Prague! It’s enough time to explore the city’s rich history, see both modern and gothic architecture, and get lost in the city’s charming narrow streets.

This is the perfect itinerary for two very busy days in Prague! You’ll see all the main attractions in the the Castle District, both the Prague Old Town and New Town, and the Lesser Town.